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Measured GFR in oncological solitary kidney: a critical parameter for precision management in onconephrology
Abstract Background and Aims Chronic kidney disease (CKD) and acute kidney injury (AKI) are among the most significant long-term complications following radical nephrectomy (RN) for renal masses. In clinical practice, precise renal function assessment is crucial to minimize these risks, particularly for patients with an oncological solitary kidney (SK), where management largely depends on glomerular filtration rate (GFR) values. While estimated GFR (eGFR) is the most commonly
Maulinkumar Patel
Dec 7, 20252 min read


Nephrotoxicity of Conventional Chemotherapeutics: Part II — Non-Platinum Agents and Miscellaneous Nephrotoxic Drugs
Abstract While modern anticancer therapies have significantly improved survival in patients with cancer, their success is often hindered by unintended side effects and toxicities, particularly to the kidneys. Many conventional chemotherapeutic agents, despite their efficacy, exert nephrotoxic effects that can result in short- and long-term adverse kidney outcomes. This review critically examines the renal implications of non-platinum alkylating agents and other less commonly
Maulinkumar Patel
Dec 7, 20251 min read


Nephrotoxicity of Conventional Chemotherapeutics: Part I - Platinum Compounds and Antimetabolite Agents
Abstract Anticancer therapies have significantly improved survival rates in patients with cancer; however, despite prophylactic measures, many conventional chemotherapeutic agents cause acute and chronic kidney injury. This review provides a comprehensive analysis of the incidence, characteristics, and management of platinum-based and anti-metabolite chemotherapeutic agent-associated nephrotoxicity based on the existing literature. Understanding the profiles of these onconeph
Maulinkumar Patel
Dec 7, 20251 min read


Medications-Related Adverse Events and Discordancies in Cystatin C–Based vs Sr Creatinine–Based GFR
Question: What are the implications of discordancies between estimated glomerular filtration rates (eGFR) derived from serum creatinine...
Mina shaker
Aug 8, 20231 min read


Cancer as an outcome in recipients of kidney transplant
Scope and consistency of cancer outcomes reported in randomized trials in kidney transplant recipients Eric H. Au, Germaine Wong, Allison...
Omar Mamlouk
Nov 9, 20222 min read


Favorable Long term kidney outcomes of bevacizumab-associated kidney adverse effects
Srinivasan V, Kfoury B, Ahmad S, Cohen J, Geara AS. Long term outcomes of bevacizumab-associated kidney adverse effects. Journal of...
Omar Mamlouk
Oct 26, 20221 min read


Increased cancer risk and cancer related mortality in CKD patients
Cancer Risk and Mortality in Patients With Kidney Disease: A Population-Based Cohort Study Abhijat Kitchlu, Jennifer Reid, Nivethika...
Omar Mamlouk
Oct 21, 20222 min read


Acute Kidney Injury in Critically Ill Patients with Cancer
Shruti Gupta , Prakash Gudsoorkar, and Kenar D. Jhaveri Abstract Advances in cancer therapy have significantly improved overall patient...
Omar Mamlouk
Oct 21, 20221 min read


Outcomes of CD19 targeted CAR T-cell Therapy for Patients with Reduced Renal Function Including ....
Transplantation and Cellular Therapy Anthony C. Wood Ariel Perez Perez Brian Arciola Kedar Patel Grace Johnson Elizabeth DiMaggio...

Paul Hanna
Oct 1, 20222 min read


Comparison of short- and long-term adverse kidney outcomes after CAR-T and auto-HSCT for DLBCL
Paul Hanna, Ian Strohbehn, Daiana Moreno1 Destiny Harden, Harish Seethapathy, Shruti Gupta, Meghan Lee, Tianqi Ouyang Matthew Frigault,...

Paul Hanna
Aug 3, 20221 min read


Acute kidney injury caused by haplostorm after allogenic hematopoietic stem cell transplant
Paul Hanna, Ian Strohbehn, Qiyu Wang, Matthew Frigault, Meghan E Sise For full article: https://www.nature.com/articles/s41409-022-01720-...

Paul Hanna
Jun 4, 20221 min read


F4/80hi Resident Macrophages Contribute to Cisplatin-Induced Renal Fibrosis
Sophia M. Sears, Alexis A. Vega, Zimple Kurlawala, Gabrielle B. Oropilla, Austin Krueger, Parag P. Shah, Mark A. Doll, Robert Miller,...
Kaitlin Harold
Feb 10, 20222 min read


Onconephrology: The intersections between the kidney and cancer
Mitchell H. Rosner, Kenar D. Jhaveri, Blaithin A. McMahon, Mark A.Perazella Full article link: https://acsjournals.onlinelibrary.wiley.c...
Kenar Jhaveri
Dec 20, 20211 min read


Clinicopathologic Features of Acute Kidney Injury Associated with Cyclin-Dependent Kinase 4/6 inhib
Shruti Gupta, Tiffany Caza, Sandra M. Herrmann, Vipulbhai C. Sakhiya, Kenar D. Jhaveri. For full article: https://pubmed.ncbi.nlm.nih.gov...
Kaitlin Harold
Dec 14, 20211 min read


Kidney toxicity of the BRAF-kinase inhibitor vemurafenib is driven by . . .
off-target ferrochelatase inhibition. Bai Y, Kim JY, Bisunke B, Jayne LA, Silvaroli JA, Balzer MS, Gandhi M, Huang KM, Sander V, Prosek...
Kaitlin Harold
Dec 14, 20211 min read


Hypophosphatemia in cancer patients
Adhikari S, Mamlouk O, Rondon-Berrios H, Workeneh BT. For full article: https://pubmed.ncbi.nlm.nih.gov/34754427/ Abstract Dysregulation...
Kaitlin Harold
Dec 14, 20211 min read


Acute kidney injury in patients treated with immune checkpoint inhibitors
Gupta S, Short SAP, Sise ME, ICPi-AKI Consortium Investigators, et al. For full article: http://dx.doi.org/10.1136/jitc-2021-003467...
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Dec 11, 20212 min read
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